The Osaka Museum of Housing and Living focuses on the history of housing and daily life in Osaka. Its highlight is a full-scale recreation of an Edo-period Osaka townscape, located near the Tenjinbashisuji shopping arcade. Visitors can walk through the reconstructed streets.
The Osaka Museum of History traces the city's history from the ancient Naniwa Palace through the modern era. Housed in a tall building just west of Osaka Castle, its upper floors overlook the castle and the former palace site. Exhibits include period dioramas and artifacts.
Abeno Harukas Art Museum sits inside Abeno Harukas, one of Japan's tallest skyscrapers in the Abeno district of Osaka. Located on the 16th floor, it is a city-center museum that hosts rotating special exhibitions. The same building also houses an observation deck and department store.
The Osaka Contemporary Art Center was a public art facility run by Osaka Prefecture focusing on contemporary art. It is known as a public art base that hosted exhibitions by regional artists and supported contemporary art activities.
The Yuki Museum of Art is a museum whose collection centers on works related to the tea ceremony. Located in central Osaka, it is known for displaying tea bowls, tea utensils, and paintings connected to Japanese tea culture.
The Mint Museum is run by the Japan Mint and presents the history of coin and medal production. It stands within the Mint's grounds in Osaka, an area also famous for its springtime cherry-blossom walk known as the Sakura no Toorinuke. Exhibits cover currency and minting.
The Shiba Ryotaro Memorial Museum honors the celebrated Japanese novelist Shiba Ryotaro. Located in Higashiosaka, it preserves the author's house and study, and is notable for a large book-wall gallery designed by architect Tadao Ando.
The Osaka City Sewerage Science Museum is a science museum where visitors learn about how sewerage systems work and why they matter. It offers hands-on exhibits on the water cycle and urban sanitation, designed so children and families can understand the treatment process.
The Amagasaki City Museum of History covers the history and culture of Amagasaki in Hyogo Prefecture. It is known for occupying a repurposed former school building and preserves and displays archaeological and folk materials of the Amagasaki area.
The Museum of Commercial History at Osaka University of Commerce is operated by the university. Located in Higashiosaka, it is a university museum that collects and exhibits materials on the history of commerce, trade, and merchant culture.

The Osaka Prefectural Archive of Kamigata Comedy and Performing Arts dealt with the Kamigata entertainment culture centered on Osaka. It collected and displayed materials on Kansai traditional arts such as manzai and rakugo, and was also known by the name "Wahha Kamigata."
The World Money Box Museum collects and displays piggy banks and money boxes from many countries. The collection originated with the Ono savings bank, and the museum stands in Amagasaki, Hyogo Prefecture, gathering money boxes from different eras and nations.